Search results for "Taxonomic classification"

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Taxonomic Classification for Living Organisms Using Convolutional Neural Networks

2017

Taxonomic classification has a wide-range of applications such as finding out more about evolutionary history. Compared to the estimated number of organisms that nature harbors, humanity does not have a thorough comprehension of to which specific classes they belong. The classification of living organisms can be done in many machine learning techniques. However, in this study, this is performed using convolutional neural networks. Moreover, a DNA encoding technique is incorporated in the algorithm to increase performance and avoid misclassifications. The algorithm proposed outperformed the state of the art algorithms in terms of accuracy and sensitivity, which illustrates a high potential f…

0301 basic medicinelcsh:QH426-470Taxonomic classificationADNCodificació Teoria de laBiologyBioinformaticsMachine learningcomputer.software_genreDNA; genes; taxonomic classification; convolutional neural networks; encodingConvolutional neural networkArticle03 medical and health sciences0302 clinical medicineBiologia -- ClassificacióEncoding (memory)convolutional neural networksGeneticstaxonomic classificationSensitivity (control systems)genesGenetics (clinical)ta113Biology -- Classificationbusiness.industryBiological classificationCoding theoryDNAencodinglcsh:Genetics030104 developmental biologyGenes030220 oncology & carcinogenesisEncodingConvolutional neural networksArtificial intelligenceCoding theorybusinesscomputerGens
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Comparison of different assembly and annotation tools on analysis of simulated viral metagenomic communities in the gut

2013

Abstract Background The main limitations in the analysis of viral metagenomes are perhaps the high genetic variability and the lack of information in extant databases. To address these issues, several bioinformatic tools have been specifically designed or adapted for metagenomics by improving read assembly and creating more sensitive methods for homology detection. This study compares the performance of different available assemblers and taxonomic annotation software using simulated viral-metagenomic data. Results We simulated two 454 viral metagenomes using genomes from NCBI's RefSeq database based on the list of actual viruses found in previously published metagenomes. Three different ass…

Taxonomic classificationComputational biologyBiologyGenomeContig MappingContig MappingUser-Computer Interface03 medical and health sciencesAnnotationDatabases GeneticGeneticsRefSeqCluster AnalysisHumansComputer SimulationTaxonomic rank030304 developmental biologyDe Bruijn sequenceInternetPrincipal Component Analysis0303 health sciencesBacteriaContigChimera identification030306 microbiologyComputational BiologyFunctional annotationViral metagenomeIntestinesAssembler performanceMetagenomicsVirusesMetagenomicsAlgorithmsResearch ArticleBiotechnologyBMC Genomics
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